Endemic infections, vaccinations, and variability of SARS-COV2 worldwide epidemiology: A cross-sectional study

J Med Virol. 2021 May;93(5):3105-3112. doi: 10.1002/jmv.26875. Epub 2021 Mar 1.

Abstract

The present article aims to analyze epidemiologic aspects of the novel coronavirus pandemic (COVID-19) over different countries across the globe. While analyzing the overall spread of the disease, clusters of countries could be identified where the population-adjusted number of cases and mortality rates (MRs) were significantly different from the others. To draw a comparison over the countries at the same stage of infection, the nature and spread of the infection was evaluated at the 90th day of the pandemic for each country. It was observed that the countries with prevalent malarial transmission tended to have lesser population-adjusted COVID-19 caseloads. It was further observed that high population coverage of the Bacillus Calmette-Guérin vaccination was negatively associated with population-adjusted caseloads and MRs due to COVID-19. The present cross-sectional study is an attempt to bring in several social, economic, and structural confounders into understanding of the nature and spread of this novel pandemic globally.

Keywords: SARS coronavirus; disease control; endemic infection; epidemiology; vaccines/vaccine strains; virus classification.

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / immunology*
  • Cross-Sectional Studies
  • Endemic Diseases
  • Global Health
  • Humans
  • Population Surveillance
  • SARS-CoV-2*
  • Vaccination

Substances

  • COVID-19 Vaccines