Current and future best practice in imaging, staging, and response assessment for Non-Hodgkin's lymphomas: the Specialist Integrated Haematological Malignancy Imaging Reporting (SIHMIR) paradigm shift

S Zafar; R K Sharma; J Cunningham; P Mahalingam; A D Attygalle; N Khan; D Cunningham; D El-Sharkawi; S Iyengar; B Sharma

doi:10.1016/j.crad.2020.12.022

Current and future best practice in imaging, staging, and response assessment for Non-Hodgkin's lymphomas: the Specialist Integrated Haematological Malignancy Imaging Reporting (SIHMIR) paradigm shift

Clin Radiol. 2021 May;76(5):391.e1-391.e18. doi: 10.1016/j.crad.2020.12.022. Epub 2021 Feb 10.

Authors

S Zafar¹, R K Sharma², J Cunningham³, P Mahalingam³, A D Attygalle³, N Khan⁴, D Cunningham³, D El-Sharkawi³, S Iyengar⁵, B Sharma⁶

Affiliations

¹ Department of Radiology, The Royal Marsden NHS Trust, London, UK. Electronic address: sarazafar@nhs.net.
² College of Medicine and Health, University of Exeter, UK.
³ The Lymphoma Unit, The Royal Marsden NHS Trust, London, UK.
⁴ Department of Radiology, The Royal Marsden NHS Trust, London, UK.
⁵ The Lymphoma Unit, The Royal Marsden NHS Trust, London, UK; The Institute of Cancer Research, London, UK.
⁶ Department of Radiology, The Royal Marsden NHS Trust, London, UK; The Lymphoma Unit, The Royal Marsden NHS Trust, London, UK.

PMID: 33579517
DOI: 10.1016/j.crad.2020.12.022

Abstract

Non-Hodgkin's lymphoma (NHL) encompasses over 40 different haematological malignancies, including low and high-grade neoplasms, such as follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) respectively. A key clinical issue in the context of NHL is delayed and inaccurate diagnosis, which contributes adversely to patient morbidity and mortality. This article will address relevant imaging aspects, with particular reference to advancements in NHL imaging, including computed tomography (CT), integrated positron-emission tomography (PET)-CT, and magnetic resonance imaging (MRI). We provide multiparametric (anato-functional) imaging display items, including histological correlation. We will also introduce our original concept of "Specialist Integrated Haematological Malignancy Imaging Reporting" (SIHMIR), a paradigm shift in lymphoma radiology.

Publication types

Review

MeSH terms

Humans
Lymphoma, Non-Hodgkin / diagnostic imaging*
Lymphoma, Non-Hodgkin / pathology*
Magnetic Resonance Imaging / methods*
Neoplasm Staging
Positron Emission Tomography Computed Tomography / methods*
Radiology Information Systems*
Tomography, X-Ray Computed / methods*