Early life factors and COVID-19 infection in England: A prospective analysis of UK Biobank participants

Altug Didikoglu; Asri Maharani; Neil Pendleton; Maria Mercè Canal; Antony Payton

doi:10.1016/j.earlhumdev.2021.105326

Early life factors and COVID-19 infection in England: A prospective analysis of UK Biobank participants

Early Hum Dev. 2021 Apr:155:105326. doi: 10.1016/j.earlhumdev.2021.105326. Epub 2021 Feb 4.

Authors

Altug Didikoglu¹, Asri Maharani², Neil Pendleton³, Maria Mercè Canal³, Antony Payton⁴

Affiliations

¹ Division of Neuroscience & Experimental Psychology, The University of Manchester, UK. Electronic address: altug.didikoglu@manchester.ac.uk.
² Division of Midwifery, Nursing and Social Care, The University of Manchester, UK.
³ Division of Neuroscience & Experimental Psychology, The University of Manchester, UK.
⁴ Division of Informatics, Imaging & Data Sciences, The University of Manchester, UK.

Abstract

This study aims to examine whether maternal smoking, birth weight, birth month and breastfeeding are associated with COVID-19 infection and hospitalisation. Maternal smoking was positively associated with COVID-19 infection. Breastfeeding was negatively associated with COVID-19 infection. The odds of being hospitalised due to COVID-19 were higher among those who had lower birthweight and mothers who were smoking during pregnancy.

Keywords: COVID-19; Early life factors; UK Biobank.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Biological Specimen Banks
Breast Feeding*
COVID-19 / etiology
COVID-19 / physiopathology*
COVID-19 / therapy
Cohort Studies
Female
Hospitalization*
Humans
Infant, Low Birth Weight
Longitudinal Studies
Male
Middle Aged
Risk Factors
Smoking / adverse effects*
United Kingdom