[Diabetes mellitus and high blood pressure over risk in HIV-infected people followed at Souro Sanou University Hospital Day Hospital, Bobo-Dioulasso 2018]

A Hema; A Poda; J-B Tougouma; C Meda; F Kabore; J Zoungrana; E Kamoule; I Sore; G Bado; A-S Ouedraogo; A-B Sawadogo; A Millogo

doi:10.1016/j.respe.2020.12.001

[Diabetes mellitus and high blood pressure over risk in HIV-infected people followed at Souro Sanou University Hospital Day Hospital, Bobo-Dioulasso 2018]

Rev Epidemiol Sante Publique. 2021 Apr;69(2):72-77. doi: 10.1016/j.respe.2020.12.001. Epub 2021 Feb 6.

[Article in French]

Authors

A Hema¹, A Poda², J-B Tougouma³, C Meda⁴, F Kabore⁵, J Zoungrana², E Kamoule⁶, I Sore⁷, G Bado⁷, A-S Ouedraogo⁷, A-B Sawadogo⁷, A Millogo⁸

Affiliations

¹ Hôpital de jour du service de maladies infectieuses, CHU Souro Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso. Electronic address: hemaarsene@yahoo.fr.
² Hôpital de jour du service de maladies infectieuses, CHU Souro Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso; Institut national des sciences de la santé, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
³ Service de cardiologie, CHU Souro Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso; Institut national des sciences de la santé, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
⁴ Institut national des sciences de la santé, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
⁵ Institut national de santé publique, Ouagadougou, Burkina Faso.
⁶ Service d'hépato-gastroentérologie, CHU Souro Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
⁷ Hôpital de jour du service de maladies infectieuses, CHU Souro Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
⁸ UFR/Sciences de la santé, Université Joseph Ki Zerbo, Ouagadougou, Burkina Faso.

PMID: 33563493
DOI: 10.1016/j.respe.2020.12.001

Abstract

Background: Non-communicable diseases (NCDs) represent the leading causes of death worldwide. HIV also increases the risk of developing NCDs including diabetes mellitus and hypertension.

Methods: A cross-sectional study, based on an analysis of the cohort database of the day hospital of the Souro Sanou teaching hospital in Bobo-Dioulasso (Burkina Faso). Diabetes mellitus was defined by the undergoing of anti-diabetic treatment or two successive measurements of fasting blood sugar above 7mmol/l and high blood pressure by the undergoing of antihypertensive treatment or two successive measurements of blood pressure above 140/90mmHg. Comparison of the frequency of diabetes and hypertension in the people living with HIV/AIDS (PLWHA) population on antiretroviral therapy (ART) with that of the general population of Burkina Faso was made by indirect standardization according to age and gender.

Results: A total of 4259 patients including 3148 women (73.9%) were included in this study. The median age of the patients was 45 years (IQR: 38-52); the median body mass index (BMI) was 19.6kg/m² (IQR: 15.4 - 22.7) and 48.3% of patients had a BMI≥25kg/m². The median CD4 count was 590 cells/mm³ (IQR: 417-785). The median ART duration was 8.2 years (IQR: 4.7-11.2). The majority of patients (82.9%) were on treatment combinations consisting in 2 INTI+1 NNRTI. Prevalence of hypertension was 39.8%; it was statistically higher in men than in women (45.8% versus 37.8%). Prevalence of hypertension was 87.0% higher in the PLWHA population than among same-sex and same-age subjects in the general population. Prevalence of diabetes mellitus was 7.3%. Diabetes mellitus was more common in men than in women (10.1% versus 6.3%; P<10^-3). Prevalence of diabetes mellitus was 36.0% higher in the PLWHA population than among same-sex and same-age subjects in the general population.

Conclusion: Prevalence of diabetes mellitus and hypertension was higher among PLHWA undergoing ART than in the general population. Care for the PLHWA population should more widely include NCD treatment.

Keywords: ART; ARV; Bobo-Dioulasso; Burkina Faso; Diabetes; Diabète; HIV; HTA; Hypertension; VIH.

MeSH terms

Adult
Burkina Faso / epidemiology
Cross-Sectional Studies
Diabetes Mellitus* / epidemiology
Female
HIV Infections* / complications
HIV Infections* / drug therapy
HIV Infections* / epidemiology
Hospitals, University
Humans
Hypertension* / epidemiology
Male
Middle Aged