Home fetal heart rate monitoring in anti Ro/SSA positive pregnancies: Literature review and case report

Eur J Obstet Gynecol Reprod Biol. 2021 Apr:259:1-6. doi: 10.1016/j.ejogrb.2021.01.031. Epub 2021 Jan 28.

Abstract

Anti-Ro/SSA antibodies are associated with a risk of 1-2 % to develop complete atrioventricular block (AVB) in fetuses of positive mothers. Complete AVB is irreversible, but studies suggest that anti-inflammatory treatment during the transition period from a normal fetal heart rate (FHR) to an AVB might stop this progression and restore sinus rhythm. The most efficient method for diagnostic evaluation of this arrhythmia is the pulsed-Doppler fetal echocardiography. However, weekly or bi-weekly recommended fetal echocardiographic surveillance can rarely identify an AVB in time for treatment success, also because the transition from a normal rhythm to a third degree AVB is very fast. Daily FHR monitoring in a medical facility could increase the chances of identifying the AVB onset but is difficult to realize. For this reason, an alternative method of FHR monitoring, performed directly by mothers in their home context, has been recently proposed. We present a case report utilizing this approach and review the current evidence about this condition.

Keywords: Anti-Ro/SSA antibodies; Atrioventricular block; Congenital heart block; Home monitoring fetal heart rate.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Atrioventricular Block* / diagnostic imaging
  • Echocardiography
  • Female
  • Fetus
  • Heart Rate, Fetal*
  • Humans
  • Pregnancy
  • Prenatal Care