Microbial-based Biocontrol Solutions for Fruits and Vegetables: Recent Insight, Patents, and Innovative Trends

Recent Pat Food Nutr Agric. 2021;12(1):3-18. doi: 10.2174/2212798412666210125141117.

Abstract

Background: Fruits and vegetables are susceptible to colonisation by undesired microflora, which, in pre- and post-harvest conditions, negatively impact the quality of these products, leading to a reduction of yield, shelf-life, and marketability. In the few last years, the use of microbial Biological Control Agents (BCAs) has assumed international relevance in order to control harmful microorganisms, as a promising alternative to chemical interventions.

Objective: The purpose of this review is to discuss the microbial-based solutions applicable for the biocontrol of the main microbial spoilers, phytopathogens, and human food-borne pathogens affecting fruits and vegetables during their production and storage.

Results: A comprehensive overview of the scientific literature investigating the effectiveness of BCA-based products available on the market is provided, as well as of the most recent patents protecting biotechnological applications in this field. Innovative trends are discussed, with a particular focus on the integration of BCAs to minimise spoilage phenomena and microbiological risks adopting combined approaches.

Conclusion: This study underlines the growing interest about biocontrol strategies to counteract the growth of spoilage and/or pathogenic microorganisms indicating that in the next years a considerable increase of commercial products and patents will be developed worldwide to exploit innovative biotechnological solutions in the sector.

Keywords: Biocontrol; bacteria; biological control agents (BCAs); fruits; hurdle technologies; post-harvest; pre-harvest; vegetables; yeasts.

Publication types

  • Review

MeSH terms

  • Antibiosis*
  • Bacteria / drug effects
  • Bacterial Physiological Phenomena
  • Biological Control Agents / pharmacology*
  • Food Preservation / instrumentation
  • Food Preservation / legislation & jurisprudence
  • Food Preservation / methods*
  • Fruit / chemistry*
  • Fruit / microbiology
  • Fungi / drug effects
  • Fungi / physiology*
  • Patents as Topic*
  • Plant Diseases / microbiology
  • Plant Diseases / prevention & control*
  • Vegetables / chemistry*
  • Vegetables / microbiology

Substances

  • Biological Control Agents