Gut microbial composition of elderly women born in the Japanese longevity village Ogimi

Hiroto Morita; Mutsuki Ichishima; Ipputa Tada; Hirotsugu Shiroma; Makoto Miyagi; Teppei Nakamura; Hiroshi Tanaka; Shinya Ikematsu

doi:10.12938/bmfh.2019-055

Gut microbial composition of elderly women born in the Japanese longevity village Ogimi

Biosci Microbiota Food Health. 2021;40(1):75-79. doi: 10.12938/bmfh.2019-055. Epub 2020 Aug 21.

Authors

Hiroto Morita¹, Mutsuki Ichishima¹, Ipputa Tada^{2

3}, Hirotsugu Shiroma^{2

4}, Makoto Miyagi², Teppei Nakamura¹, Hiroshi Tanaka², Shinya Ikematsu²

Affiliations

¹ Department of Microbiological Flora Technology, Core Technology Laboratories, Asahi Quality & Innovations, Ltd., 11-10-5 Fuchinobe, Sagamihara, Kanagawa 252-0206, Japan.
² Department of Bioresources Engineering, National Institute of Technology, Okinawa College, 905 Henoko, Nago, Okinawa 905-2192, Japan.
³ Present address: Department of Genetics, The Graduate University for Advanced Studies, SOKENDAI, 1111 Yata, Mishima, Shizuoka 411-8540, Japan.
⁴ Present address: School of Life Science and Technology, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.

Abstract

Ogimi is one of Japan's longevity villages and is located in Okinawa Prefecture. In this study, we focused on the elderly women living in the village, classified them into two groups based on whether or not they lived in Ogimi during the first 3 years of their lives, and compared the gut microbiota between the two groups. There were no differences in alpha and beta diversity; however, we found that the elderly women who lived in Ogimi during the first 3 years of their lives had a higher rate of Akkermansia muciniphila colonization in their guts.

Keywords: Akkermansia muciniphila; early-life environment; longevity; microbiota.