Current diagnostic and therapeutic strategies for COVID-19

Binbin Chen; Mengli Liu; Chengzhi Huang

doi:10.1016/j.jpha.2020.12.001

Current diagnostic and therapeutic strategies for COVID-19

J Pharm Anal. 2021 Apr;11(2):129-137. doi: 10.1016/j.jpha.2020.12.001. Epub 2021 Jan 13.

Authors

Binbin Chen^{1

2}, Mengli Liu¹, Chengzhi Huang^{3

4}

Affiliations

¹ College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
² School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, China.
³ Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, Southwest University, Chongqing, 400715, China.
⁴ Key Laboratory of Luminescence and Real-Time Analytical System, Chongqing Science and Technology Bureau, College of Pharmaceutical Science, Southwest University, Chongqing, 400715, China.

Abstract

The outbreak and spread of novel coronavirus disease 2019 (COVID-19) with pandemic features, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have greatly threatened global public health. Given the perniciousness of COVID-19 pandemic, acquiring a deeper understanding of this viral illness is critical for the development of new vaccines and therapeutic options. In this review, we introduce the systematic evolution of coronaviruses and the structural characteristics of SARS-CoV-2. We also summarize the current diagnostic tools and therapeutic strategies for COVID-19.

Keywords: COVID-19; Coronavirus; Diagnosis; SARS-CoV-2; Treatment.

Publication types

Review