Postmenopausal Hyperandrogenism: Evaluation and Treatment Strategies

Endocrinol Metab Clin North Am. 2021 Mar;50(1):97-111. doi: 10.1016/j.ecl.2020.12.002. Epub 2021 Jan 11.

Abstract

Evidence of clinical and/or biochemical androgen excess poses a unique differential in postmenopausal women. Some signs and symptoms of postmenopausal hyperandrogenism can be normal and attributed to the natural aging process. However, the causes of androgen excess in this group include both nontumorous and tumorous causes. Treatment of androgen excess may improve both quality of life and long-term metabolic outcomes.

Keywords: Adrenal tumor(s); Hyperandrogenism; Hyperthecosis; Ovarian tumor(s); Postmenopausal; Virilization.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Female
  • Humans
  • Hyperandrogenism* / etiology
  • Hyperandrogenism* / therapy
  • Postmenopause
  • Quality of Life
  • Testosterone

Substances

  • Testosterone