Artificial intelligence for a personalized diagnosis and treatment of atrial fibrillation

Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1337-H1347. doi: 10.1152/ajpheart.00764.2020. Epub 2021 Jan 29.

Abstract

Although atrial fibrillation (AF) is the most common cardiac arrhythmia, its early identification, diagnosis, and treatment is still challenging. Due to its heterogeneous mechanisms and risk factors, targeting an individualized treatment of AF demands a large amount of patient data to identify specific patterns. Artificial intelligence (AI) algorithms are particularly well suited for treating high-dimensional data, predicting outcomes, and eventually, optimizing strategies for patient management. The analysis of large patient samples combining different sources of information such as blood biomarkers, electrical signals, and medical images opens a new paradigm for improving diagnostic algorithms. In this review, we summarize suitable AI techniques for this purpose. In particular, we describe potential applications for understanding the structural and functional bases of the disease, as well as for improving early noninvasive diagnosis, developing more efficient therapies, and predicting long-term clinical outcomes of patients with AF.

Keywords: artificial intelligence; atrial fibrillation; classification; neural network; prediction.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Action Potentials
  • Artificial Intelligence*
  • Atrial Fibrillation / diagnosis*
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / therapy*
  • Clinical Decision-Making
  • Diagnosis, Computer-Assisted*
  • Heart Conduction System / physiopathology
  • Heart Function Tests*
  • Heart Rate
  • Humans
  • Machine Learning
  • Neural Networks, Computer
  • Pattern Recognition, Automated
  • Predictive Value of Tests
  • Therapy, Computer-Assisted*