The contributions of the left fusiform subregions to successful encoding of novel words

Abstract

The left fusiform cortex has been identified as a crucial structure in visual word learning and memory. Nevertheless, the specific roles of the fusiform subregions in word memory and their consistency across different writings have not been elaborated. To address these questions, the present study performed two experiments, in which study-test paradigm was used. Participants' brain activity was measured with fMRI while memorizing novel logographic words in Experiment 1 and novel alphabetic words in Experiment 2. A post-scan recognition memory test was then administered to acquire the memory performance. Results showed that, neural responses in the left anterior and middle fusiform subregions during encoding were positively correlated with recognition memory of novel words. Moreover, the positive brain-behavior correlations in the left anterior and middle fusiform cortex were evident for both logographic and alphabetic writings. The present findings clarify the relationship between the left fusiform subregions and novel word memory.

Keywords: Cross-writing consistency; Fusiform; Study-test paradigm; Word memory; fMRI.