The Applications of Nanopore Sequencing Technology in Pathogenic Microorganism Detection

Xiaojian Zhu; Shanshan Yan; Fenghua Yuan; Shaogui Wan

doi:10.1155/2020/6675206

The Applications of Nanopore Sequencing Technology in Pathogenic Microorganism Detection

Can J Infect Dis Med Microbiol. 2020 Dec 31:2020:6675206. doi: 10.1155/2020/6675206. eCollection 2020.

Authors

Xiaojian Zhu¹, Shanshan Yan^{2

3}, Fenghua Yuan¹, Shaogui Wan¹

Affiliations

¹ Center for Molecular Pathology, Department of Basic Medicine, Gannan Medical University, Ganzhou 341000, China.
² Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou 341000, China.
³ Department of Publication Health and Health Management, Gannan Medical University, Ganzhou 341000, China.

Abstract

Infectious diseases are major threats to human health and lead to a serious public health burden. The emergence of new pathogens and the mutation of known pathogens challenge our ability to diagnose and control infectious diseases. Nanopore sequencing technology exhibited versatile applications in pathogenic microorganism detection due to its flexible data throughput. This review article introduced the applications of nanopore sequencing in clinical microbiology and infectious diseases management, including the monitoring of emerging infectious diseases outbreak, identification of pathogen drug resistance, and disease-related microbial communities characterization.

Publication types

Review