Cardiovascular Complications of COVID-19 and Associated Concerns: A Review

Acta Cardiol Sin. 2021 Jan;37(1):9-17. doi: 10.6515/ACS.202101_37(1).20200913A.

Abstract

SARS-CoV-2 is the virus that has caused the current coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 is characterized by significantly affecting the cardiovascular system of infected patients. In addition to the direct injuries caused by the virus, the subsequent cytokine storm - an overproduction of immune cells and their activating compounds - also causes damage to the heart. The development of anti-SARS-CoV-2 treatments is necessary to control the epidemic. Despite an explosive growth in research, a comprehensive review of up-to-date information is lacking. Herein, we summarize pivotal findings regarding the epidemiology, complications, and mechanisms of, and recent therapies for, COVID-19, with special focus on its cardiovascular impacts.

Keywords: COVID-19; Cardiovascular injuries; Cytokine storm; Therapies.

Publication types

  • Review