Dehydration of D-fructose to 5-hydroxymethyl-2-furfural in DMSO using a hydrophilic sulfonated silica catalyst in a process promoted by microwave irradiation

Sandro L Barbosa; Milton de S Freitas; Wallans T P Dos Santos; David Lee Nelson; Stanlei I Klein; Giuliano Cesar Clososki; Franco J Caires; Adriano C M Baroni; Alexandre P Wentz

doi:10.1038/s41598-020-80285-2

Dehydration of D-fructose to 5-hydroxymethyl-2-furfural in DMSO using a hydrophilic sulfonated silica catalyst in a process promoted by microwave irradiation

Sci Rep. 2021 Jan 21;11(1):1919. doi: 10.1038/s41598-020-80285-2.

Authors

Sandro L Barbosa¹, Milton de S Freitas², Wallans T P Dos Santos², David Lee Nelson², Stanlei I Klein³, Giuliano Cesar Clososki⁴, Franco J Caires⁴, Adriano C M Baroni⁵, Alexandre P Wentz⁶

Affiliations

¹ Department of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Campus JK, Rodovia MGT 367 - Km 583, nº 5.000, Alto da Jacuba, Diamantina, MG, CEP 39100-000, Brazil. sandro.barbosa@ufvjm.edu.br.
² Department of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Campus JK, Rodovia MGT 367 - Km 583, nº 5.000, Alto da Jacuba, Diamantina, MG, CEP 39100-000, Brazil.
³ Department of General and Inorganic Chemistry, Institute of Chemistry, São Paulo State University-Unesp, R. Prof. Francisco Degni 55, Quitandinha, Araraquara, SP, CEP-14800-900, Brazil.
⁴ Department of Physics and Chemistry, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, São Paulo University-USP, Av. do Café s/n, Ribeirão Prêto, SP, CEP-14.040-903, Brazil.
⁵ Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição, Universidade Federal do Mato Grosso do Sul - UFMS, Av. Costa e Silva, s.n., Campo Grande, MS, 79070900, Brazil.
⁶ Centro universitário SENAI-CIMATEC, Av. Orlando Gomes, 1845, Piatã, Salvador, BA, 41650-010, Brazil.

Abstract

SiO₂-SO₃H, with a surface area of 115 m²/g, pore volumes of 0.38 cm³g^-1 and 1.32 mmol H⁺/g, was used as a 10% w/w catalyst for the preparation of 5-hydroxymethyl-2-furfural (HMF) from fructose. A conversion of 100% was achieved in a microwave reactor during 10 min at 150 °C in DMSO, with 100% selectivity for HMF, at a molar ratio of fructose: DMSO equal to 1:56. The catalyst could be re-used three times.

Publication types

Research Support, Non-U.S. Gov't