Frailty is not associated with hypertension, blood pressure or antihypertensive medication in community-dwelling older adults: A cross-sectional comparison across 3 frailty instruments

Exp Gerontol. 2021 Apr:146:111245. doi: 10.1016/j.exger.2021.111245. Epub 2021 Jan 19.

Abstract

Aim: The present study investigated whether hypertension, blood pressure, and antihypertensive therapy were associated with frailty status in community-dwelling older adults. In addition, we tested whether such associations were consistent across different frailty instruments.

Material and methods: Two-hundred older adults were enrolled in the study. Participant frailty status was determined according to a modified physical frailty phenotype (mFP), the FRAIL scale, and the Study of Osteoporotic Fracture (SOF) index. Blood pressure was assessed three times, in three different days, and mean values were used in the final analysis. Information pertaining to disease conditions and antihypertensive therapy were collected by two researchers through self-report and careful review of medical charts.

Results: No significant differences in hemodynamic parameters, hypertension diagnosis, and antihypertensive therapy were observed across frailty statuses, regardless of the frailty assessment tool used.

Conclusion: Findings of the present study indicate that hypertension, blood pressure levels and antihypertensive medication were not cross-sectionally associated with frailty status in cognitively preserved community-dwelling older adults with low prevalence of comorbidities, regardless of the tool used for frailty identification.

Keywords: Cardiovascular disease; Elderly; Hemodynamic parameters; Sarcopenia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antihypertensive Agents / therapeutic use
  • Blood Pressure
  • Cross-Sectional Studies
  • Frail Elderly
  • Frailty* / epidemiology
  • Geriatric Assessment
  • Humans
  • Hypertension* / drug therapy
  • Hypertension* / epidemiology
  • Independent Living
  • Prevalence

Substances

  • Antihypertensive Agents