Dependence of the heating effect on tissue absorption coefficient during corneal reshaping using different UV lasers: A numerical study

Phys Eng Sci Med. 2021 Mar;44(1):221-227. doi: 10.1007/s13246-021-00971-x. Epub 2021 Jan 21.

Abstract

Corneal reshaping using laser ablation effect is a well-known ophthalmologic operation implemented to correct many vision disorders. UV pulsed lasers are utilized in this surgery due to their high absorption in corneal tissue without affecting the other parts of the eye. Ideally ablation may not be associated with heat transport, since high temperature is the enemy of soft tissues. However, the thermal effect of this procedure can cause tissue damage if the temperature rises above the safety level without appropriate handling. In the present study, we try to find the trade-off between efficient ablation and minimal temperature rise. So the thermal effect on the corneal tissue after applying five UV wavelengths; 193, 210, 213, 223 and 248 nm has been simulated and investigated by solving Penne's bio-heat transfer equation using the finite element method. A 3D model of the human cornea is constructed using COMSOL Multiphysics computer software and the temperature rise is determined at the end of the laser pulse. The same spot size and pulse duration are used for each wavelength. While the absorption coefficient of the corneal tissue is the only variable as it is a wavelength dependent. The proposed results show that, the heating effect is directly proportional to the absorption coefficient. The highest recorded temperature was 259 °C at 193 nm, while, the minimum value was (70.1 °C) recorded at 248 nm at which the cornea has the lowest absorption coefficient.

Keywords: Ablation; Cornea; LASIK; UV lasers.

MeSH terms

  • Cornea*
  • Heating*
  • Humans
  • Lasers
  • Light
  • Temperature