Lower Risk of Burn Injury in Children and Adolescents with Autism Spectrum Disorder: A Nationwide Population-Based Study

Hsiang-Lin Chan; Yi-Hsuan Hsieh; Chiao-Fan Lin; Hsin-Yi Liang; Su-Shin Lee; Jun-Cheng Weng; Min-Jing Lee; Yi-Lung Chen; Vincent Chin-Hung Chen; Michael Gossop

doi:10.1007/s10803-020-04859-9

Lower Risk of Burn Injury in Children and Adolescents with Autism Spectrum Disorder: A Nationwide Population-Based Study

J Autism Dev Disord. 2023 Feb;53(2):648-655. doi: 10.1007/s10803-020-04859-9. Epub 2021 Jan 20.

Authors

Hsiang-Lin Chan^{1

2}, Yi-Hsuan Hsieh^{1

2}, Chiao-Fan Lin^{1

2}, Hsin-Yi Liang^{1

2}, Su-Shin Lee^{3

4}, Jun-Cheng Weng⁵, Min-Jing Lee^{2

6}, Yi-Lung Chen^#^{7

8}, Vincent Chin-Hung Chen^{9

10}, Michael Gossop¹¹

Affiliations

¹ Department of Child Psychiatry, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
² Department of Psychiatry, Chang Gung University, Taoyuan, Taiwan.
³ Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
⁴ Department of Surgery, Faculty of Medicine, Collage of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
⁵ Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan.
⁶ Department of Psychiatry, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
⁷ Department of Healthcare Administration, Asia University, Taichung, Taiwan.
⁸ Department of Psychology, Asia University, Taichung, Taiwan.
⁹ Department of Psychiatry, Chang Gung University, Taoyuan, Taiwan. cch1966@gmail.com.
¹⁰ Department of Psychiatry, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan. cch1966@gmail.com.
¹¹ National Addiction Centre, Institute of Psychiatry, King's College London, London, UK.

^# Contributed equally.

PMID: 33474660
DOI: 10.1007/s10803-020-04859-9

Abstract

Little research has examined burn injury in the pediatric population with autism spectrum disorder (ASD). We used data from Taiwan's National Health Insurance Research Database to identify 15,844 participants aged <18 years with ASD and 130,860 participants without ASD. Our results revealed that the hazard ratios differed across three age ranges. The ASD group had a lower risk of burn injury than the non-ASD group when they were less than 6 years of age, a higher risk from 6 years to 12 years of age, and no difference when they were older than 12 years of age. More research is required to study the characteristics and causes of burn injury in the pediatric population with ASD.

Keywords: Autism; Burn injury; Cohort study.

MeSH terms

Adolescent
Autism Spectrum Disorder* / epidemiology
Autism Spectrum Disorder* / etiology
Burns* / complications
Burns* / epidemiology
Child
Databases, Factual
Humans
Proportional Hazards Models
Risk

Grants and funding

CLRPG6G0042/Chang Gung Memorial Hospital