Correcting Higher Order Aberrations Using Image Processing

IEEE Trans Image Process. 2021:30:2276-2287. doi: 10.1109/TIP.2021.3051499. Epub 2021 Jan 26.

Abstract

Higher Order Aberrations (HOAs) are complex refractive errors in the human eye that cannot be corrected by regular lens systems. Researchers have developed numerous approaches to analyze the effect of these refractive errors; the most popular among these approaches use Zernike polynomial approximation to describe the shape of the wavefront of light exiting the pupil after it has been altered by the refractive errors. We use this wavefront shape to create a linear imaging system that simulates how the eye perceives source images at the retina. With phase information from this system, we create a second linear imaging system to modify source images so that they would be perceived by the retina without distortion. By modifying source images, the visual process cascades two optical systems before the light reaches the retina, a technique that counteracts the effect of the refractive errors. While our method effectively compensates for distortions induced by HOAs, it also introduces blurring and loss of contrast; a problem that we address with Total Variation Regularization. With this technique, we optimize source images so that they are perceived at the retina as close as possible to the original source image. To measure the effectiveness of our methods, we compute the Euclidean error between the source images and the images perceived at the retina. When comparing our results with existing corrective methods that use deconvolution and total variation regularization, we achieve an average of 50% reduction in error with lower computational costs.

MeSH terms

  • Eye / diagnostic imaging*
  • Eye / physiopathology
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Models, Biological*
  • Ophthalmologic Surgical Procedures
  • Refractive Errors / diagnostic imaging*
  • Refractive Errors / physiopathology
  • Refractive Errors / therapy
  • Vision, Ocular / physiology