Noncontact lower extremity injuries are commonly related to jumping and landing activities. This review presents an overview of relevant biomechanical variables that can be modified in training to improve jumping performance, landing mechanics, and consequently, reduce injury risks. Relevant studies from the last 2 decades in the Compendex, Pubmed, and Scopus databases were considered for this review. Studies related to jumping and landing kinetics, kinematics, injuries, performance, and/or simulation were included. The use of experimental methods as the drop jump landing and jumping countermovement are widely used to measure biomechanical variables. At the same time, there has been a continuous development of simulation models that could present results without the need for testing on human subjects, with the final objective of exploring the limits of an athlete's performance without increasing the risk of any injury. The most common injuries occur in the knee and ankle ligaments and are directly related to joint angles and moments (i.e., torque or joint loading) at the hip, ankle, and knee joints. Jumping and landing biomechanics are considerably different between male and female subjects for different experimental methods and in both cases, these kinematics factors can be improved over shorter- or longer-time training to develop a better landing strategy.