Wafer paper and ring-mounted polyglycolic acid sheet method for shielding artificial gastric floor

Minim Invasive Ther Allied Technol. 2022 Apr;31(4):548-555. doi: 10.1080/13645706.2020.1871370. Epub 2021 Jan 19.

Abstract

Background: The management of postoperative bleeding, after gastric endoscopic submucosal dissection (ESD), has become particularly important because of the recent increase in antithrombotic use. Endoscopic shielding with polyglycolic acid (PGA) sheets has been shown to be effective. However, shrinkage and early displacement of the sheet remain challenges. This study aimed to determine the efficacy and safety of our developed method, named wafer paper and ring-mounted PGA sheet (WaRP).

Material and methods: Twenty-four patients with antithrombotic uptake who underwent the WaRP method following gastric ESD were retrospectively examined. This involved the delivery of a PGA sheet wrapped in wafer paper with ring-thread, and its fixation on the gastric floor using hemoclips. The primary outcome was the technical success rate of the WaRP, and several secondary outcomes were evaluated.

Results: The technical success rate of WaRP was 100%. The procedure lasted a mean of 10.5 min (SD 6.7 min). The prevalence of complete retention at follow-up endoscopy was 83.3% (20/24). There were no WaRP-associated complications, but post-ESD hemorrhage occurred in two patients undergoing hemodialysis (8.3%).

Conclusions: The WaRP method is a simple and reliable means of PGA sheet delivery and placement that reduces the incidence of post-ESD hemorrhage.

Keywords: Polyglycolic acid sheet; delivery method; wafer paper.

MeSH terms

  • Endoscopy, Gastrointestinal
  • Fibrinolytic Agents
  • Gastric Mucosa / surgery
  • Humans
  • Polyglycolic Acid*
  • Postoperative Hemorrhage / epidemiology
  • Postoperative Hemorrhage / prevention & control
  • Retrospective Studies
  • Stomach Neoplasms* / surgery

Substances

  • Fibrinolytic Agents
  • Polyglycolic Acid