Dental radiation dosimetric maps from intensity-modulated radiation therapy planning for head and neck cancers

Head Neck. 2021 May;43(5):1428-1439. doi: 10.1002/hed.26611. Epub 2021 Jan 15.

Abstract

Background: The purpose of this study was to create dental radiation maps to calculate the mean dose to individual teeth, maxilla and mandible using intensity-modulated radiation therapy (IMRT).

Methods: Eighteen common clinical settings were chosen. Radiation plans were extracted, and each tooth was contoured at its junction with the gingiva and labeled based on the Universal/American numbering system.

Results: All patients were treated with prescribed doses of 50-70 Gy in 1.66-2 Gy/fraction. Patients receiving mean doses >50 Gy to the teeth, mandible, and maxilla included those with advanced tumors of the oral cavity and gross lymphadenopathy of level 1b.

Conclusion: We believe this to be the first study generating dosimetric maps of estimated doses to each tooth and each third of the mandible and the maxilla for common examples of head and neck cancer faced by radiation oncologists. Adoption of these dental maps may help improve clinical workflow efficiency.

Keywords: cancer; dental; head; intensity-modulated radiation therapy; maps; neck; osteoradionecrosis; squamous cell carcinoma; teeth.

MeSH terms

  • Head and Neck Neoplasms* / radiotherapy
  • Humans
  • Mandible
  • Radiometry
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy, Intensity-Modulated*