Epidemiology of Hospitalized Intussusception Cases from Northern States in India

Indian J Pediatr. 2021 Mar;88(Suppl 1):118-123. doi: 10.1007/s12098-020-03609-0. Epub 2021 Jan 16.

Abstract

Objective: To describe epidemiology of intussusception post-introduction of the rotavirus vaccine.

Methods: Hospital-based active surveillance system was set up in three tertiary care hospitals in Chandigarh and Haryana, India, to enroll children <2 y of age admitted with intussusception as per Brighton Collaboration Level-I criteria. The clinical characteristics, treatment modalities, seasonal trends, and outcome of the illness episodes were described.

Results: A total of 224 cases were reported. Majority were males (71%) and infants (69.5%). Number of intussusception was more in summer season. Location of intussusception was ileo-colic in 85% of the cases. Nearly 54% cases were treated conservatively and 46% needed surgical intervention.

Conclusion: Surveillance data provided the epidemiological description of intussusception cases post-introduction of the rotavirus vaccine in northern India. This data could be used to assess the impact of vaccine and safety with a special focus on intussusception.

Keywords: Epidemiology; Intussusception; Rotavirus; Rotavirus vaccine.

MeSH terms

  • Child
  • Female
  • Humans
  • Incidence
  • India / epidemiology
  • Infant
  • Intussusception* / epidemiology
  • Intussusception* / therapy
  • Male
  • Retrospective Studies
  • Rotavirus Infections* / epidemiology
  • Rotavirus Infections* / therapy
  • Rotavirus Vaccines*
  • Vaccination

Substances

  • Rotavirus Vaccines