Intention to accept pertussis vaccination among Chinese people older than age 5

Hum Vaccin Immunother. 2021 Jun 3;17(6):1686-1692. doi: 10.1080/21645515.2020.1849517. Epub 2021 Jan 15.

Abstract

Background: The intention of Chinese people older than age 5 to accept the pertussis vaccination is unknown, which is important for the future design of an effective pertussis vaccination program in China.Method: We conducted a cross-sectional survey among people older than age 5 in China. A 24-item questionnaire was used to explore the determinants of intention to accept a pertussis vaccination, and for children and adolescents (≦15 years old), their guardian was required to help answer the questionnaire on their behalf. Univariate and multivariate logistic regression was used to analyze the influencing factors of intention.Results: A total of 3,041 individuals participated in our survey and 3025 completed the questionnaire, among which 1938 (64.07%) reported a positive intention to be vaccinated. A multiple logistic regression analysis revealed that the main positive factors for the intention to accept pertussis vaccination were younger age (Odd ratio [OR] 0.838, P < .001), higher educational attainment (OR 1.171, P = .002), no hospitalization because of the most recent cough (OR 2.468, P < .001), awareness about pertussis (OR 1.958, P < .001), and consideration of pertussis vaccination to be safe (OR 1.450, P = .026).Conclusion: There is a relatively high level of intention to receive the pertussis vaccine among people older than age 5 in China. Future pertussis vaccination strategies geared at them should consider focusing on middle-aged and older individuals and those with a low education as well as strengthen the promotion of disease characteristics, vaccine effectiveness, and safety.

Keywords: Pertussis; cross-sectional survey; intention; vaccination program.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Aged
  • Child
  • Child, Preschool
  • China
  • Cross-Sectional Studies
  • Humans
  • Intention
  • Middle Aged
  • Pertussis Vaccine
  • Surveys and Questionnaires
  • Vaccination
  • Whooping Cough*

Substances

  • Pertussis Vaccine

Grants and funding

This work was supported by the Medical Health Science and Technology Project of Zhejiang Province, China under Grants [number 2019KY052 and 2019KY059], National Natural Science Foundation of China (NSFC) [grant number 81973106], Beijing Municipal Natural Science Foundation [grant number 19L2060].