Identification of novel anti-tumor therapeutic target via proteomic characterization of ubiquitin receptor ADRM1/Rpn13

Blood Cancer J. 2021 Jan 13;11(1):13. doi: 10.1038/s41408-020-00398-9.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • CRISPR-Cas Systems
  • HCT116 Cells
  • Humans
  • Intracellular Signaling Peptides and Proteins / genetics
  • Intracellular Signaling Peptides and Proteins / metabolism*
  • Multiple Myeloma / genetics
  • Multiple Myeloma / metabolism
  • Neoplasms / genetics
  • Neoplasms / metabolism*
  • Proteasome Endopeptidase Complex / metabolism
  • Proteolysis
  • Proteomics
  • Ubiquitin / metabolism

Substances

  • ADRM1 protein, human
  • Intracellular Signaling Peptides and Proteins
  • Ubiquitin
  • Proteasome Endopeptidase Complex