Application of a novel carboxymethyl cellulose-based Mohs sol-gel on malignant wounds in three dogs

J Vet Med Sci. 2021 Mar 11;83(3):385-389. doi: 10.1292/jvms.20-0670. Epub 2021 Jan 13.

Abstract

The preparation of modified Mohs paste, commonly used for malignant wounds, requires time and effort. Moreover, metal-containing liquid waste is generated when malignant wounds are scrubbed. Therefore, we previously changed the base material of the modified Mohs paste from zinc oxide starch powder to carboxymethyl cellulose (CMC). The novel modified Mohs paste based on CMC (moM-CMC sol) may reduce these disadvantages. In the present study, the moM-CMC sol was applied to malignant tumors in three dogs to manage bleeding and malodor. The moM-CMC sol transitioned into a gel on the tumors within an hour of application and could be easily removed. The symptoms resolved in all cases. The moM-CMC sol could be beneficial for dogs with malignant wounds.

Keywords: Mohs paste; carboxymethyl cellulose; dog; malignant wound; zinc chloride.

MeSH terms

  • Animals
  • Carboxymethylcellulose Sodium
  • Dog Diseases* / drug therapy
  • Dog Diseases* / surgery
  • Dogs
  • Neoplasms* / veterinary
  • Starch

Substances

  • Starch
  • Carboxymethylcellulose Sodium