Bioavailability and antioxidant activity of nanotechnology-based botanic antioxidants

J Food Sci. 2021 Feb;86(2):284-292. doi: 10.1111/1750-3841.15582. Epub 2021 Jan 12.

Abstract

Botanic bioactive substances have issues with their solubility, stability, and oral bioavailability in the application, which could be improved by nanotechnologies. In another hands, green synthesis of nanoparticles (NPs) with plant extract is also a promising technology for preparation of NPs due to its safety advantage, yet the bioactive botanic substances that could be more than the assistant of the green synthesis of NPs. Based on the above concerns, this review summarized the preparation of botanic NPs with various plant extract, their solubility, stability, and oral bioavailability; specific attention has been paid to the botanic Ag/Au NPs, their capacity of antioxidant, bioavailability, antimicrobial, anti-inflammatory, and anticancer.

Keywords: antimicrobial; bioavailability; botanic antioxidant; nanoparticles.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antineoplastic Agents
  • Antioxidants / chemistry
  • Antioxidants / pharmacokinetics*
  • Biological Availability
  • Gold
  • Green Chemistry Technology*
  • Metal Nanoparticles / chemistry
  • Nanotechnology*
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacokinetics*
  • Plant Extracts / chemistry
  • Plants
  • Silver
  • Solubility

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antineoplastic Agents
  • Antioxidants
  • Phytochemicals
  • Plant Extracts
  • Silver
  • Gold