Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol

Jing Wang; Sen Liu; Jiahuan Luo; Shaogang Hou; Haixiang Song; Yongsheng Niu; Chuanxiang Zhang

doi:10.3389/fchem.2020.594093

Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol

Front Chem. 2020 Dec 8:8:594093. doi: 10.3389/fchem.2020.594093. eCollection 2020.

Authors

Jing Wang^{1

2}, Sen Liu¹, Jiahuan Luo¹, Shaogang Hou¹, Haixiang Song¹, Yongsheng Niu¹, Chuanxiang Zhang²

Affiliations

¹ Henan Joint International Research Laboratory of Nanocomposite Sensing Materials, School of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang, China.
² Henan Key Laboratory of Coal Green Conversion, College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, China.

Abstract

An electrochemical sensor for paracetamol is executed by using conductive MOF (NiCu-CAT), which is synthesized by 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) ligand. The utility of this 2D NiCu-CAT is measured by the detection of paracetamol, p-stacking within the MOF layers is essential to achieve high electrical conductivity, redox activity, and catalytic activity. In particular, NiCu-CAT demonstrated detection Limit of determination near 5μM for paracetamol through a wide concentration range (5-190 μM). The NiCu-CAT/GCE exhibits excellent reproducibility, stability, and interference for paracetamol.

Keywords: NiCu-CAT; amperometric; conductive MOF; paracetamol detection; sensor.