To bee or not to bee? The bee extract propolis as a bioactive compound in the burden of lifestyle diseases

Nutrition. 2021 Mar:83:111094. doi: 10.1016/j.nut.2020.111094. Epub 2020 Nov 24.

Abstract

Propolis is a polyphenolic plant resin collected by bees to protect hives against pathogens and temperature drop. It exhibits antibacterial, antioxidant, and antiinflammatory properties. Propolis has been reported to possess antidiabetic properties and display beneficial effects against cardiovascular disease, gut dysbiosis, and chronic kidney disease. It has an excellent clinical safety profile, with no known toxic effects described so far. In this review, we discuss the salutogenic effects of propolis, with particular reference to modulating notable features of chronic kidney disease, notably those involving cardiovascular risks.

Keywords: Chronic kidney disease; Gut microbiota; Inflammation; Oxidative stress; Propolis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents*
  • Bees
  • Dysbiosis
  • Life Style
  • Plant Extracts
  • Propolis*

Substances

  • Anti-Infective Agents
  • Plant Extracts
  • Propolis