Brucellosis screening and follow-up of seropositive asymptomatic subjects among household members of shepherds in China

Eur J Clin Microbiol Infect Dis. 2021 Jun;40(6):1325-1328. doi: 10.1007/s10096-020-04115-z. Epub 2021 Jan 7.

Abstract

To measure the seroprevalence of high-exposure populations in brucellosis endemic areas and report the outcome and duration of seropositive asymptomatic subjects, we screened 595 family members of shepherds in Jilin Province, China and then followed up 15 seropositive asymptomatic subjects for 18 months. We found that the seropositive rate of 15.5%. Nearly half of seropositive asymptomatic subjects (7/15) developed into brucellosis in the short term; others were still seropositive asymptomatic or had decreased SAT titer in a longer time.

Keywords: follow-up; seropositive asymptomatic; shepherds.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Animals
  • Antibodies, Bacterial / blood*
  • Asymptomatic Diseases / epidemiology
  • Bacterial Zoonoses / blood*
  • Bacterial Zoonoses / epidemiology
  • Bacterial Zoonoses / transmission
  • Brucella / immunology*
  • Brucella / isolation & purification
  • Brucellosis / blood*
  • Brucellosis / diagnosis
  • Brucellosis / epidemiology
  • Brucellosis / transmission
  • Child
  • China / epidemiology
  • Cross-Sectional Studies
  • Family
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Seroepidemiologic Studies
  • Sheep
  • Sheep Diseases / microbiology
  • Young Adult

Substances

  • Antibodies, Bacterial