Instrument-based screening for amblyopia risk factors in a primary care setting in children aged 18 to 30 months

Eur J Pediatr. 2021 May;180(5):1521-1527. doi: 10.1007/s00431-020-03904-0. Epub 2021 Jan 7.

Abstract

Amblyopia is the leading cause of vision impairment in children, and its early detection can avoid irreversible consequences for a child's visual ability. In this prospective study, to detect amblyopia risk factors, we examined patients aged 18 to 30 months in primary care settings. Patients were referred to an ophthalmologist for confirmation. The main aims were to detect amblyogenic risk factors and to assess the usefulness of a photoscreener in such settings. Out of 453 patients, 42 (9.3%) presented visual alterations according to the photoscreener, with astigmatism being the most common. The instrument had good sensitivity (89%) and specificity (91%), with a positive predictive value of 76% and a negative predictive value of 96%. Overall, 38% of the patients required follow-up, and 47% needed glasses. The automated screening device allowed these children to be diagnosed at an early stage.Conclusions: The use of a photoscreener to screen 2-year-old children in primary care settings was helpful and accurate. What is Known: • Early detection of amblyopic risk factors is important to avoid vision defects. However, it is very difficult to measure visual acuity using visual charts in children younger than 4 years old. What is New: • Instrument-based screening in children aged 18 to 30 months allows excellent detection of early amblyopia risk factors in primary care settings.

Keywords: Amblyopia; Children; Photoscreening; Primary care; Visual defects.

MeSH terms

  • Amblyopia* / diagnosis
  • Child, Preschool
  • Humans
  • Primary Health Care
  • Prospective Studies
  • Risk Factors
  • Sensitivity and Specificity
  • Vision Screening*

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