Biogenesis and Application of Nickel Nanoparticles: A Review

Curr Pharm Biotechnol. 2021;22(6):808-822. doi: 10.2174/1389201022999210101235233.

Abstract

Biogenic synthesis of Nanoparticles (NPs) is attractive due to their ecological benefits and cheap, rapid, and sustainable nature. Among them, Nickel Oxide NPs (NiO-NPs) are acquired for their varied catalytic and clinical applications, as they have antibacterial, antifungal, cytotoxic, anticancer, antioxidant, remediation, and enzyme inhibition properties. Though several chemical-dependent methods were applied for the fabrication of nanoparticles, due to their substantial disadvantages, mainly toxicity and higher cost synthesis methods, the more secure, greener, eco-friendly, cost-effective, and synthetic methods are in demand. Greener approaches can take away the arduousness and complications of physicochemical methods. The present review is aimed at displaying the recent advancement related to the catalytic activity, antimicrobial activity, cytotoxicity, and antioxidant application of green synthesized Nickle. In this study, nickle oxide nanoparticles have been highlighted along with their sustainable synthesis options.

Keywords: Biological material; antimicrobial activity; antioxidant; catalytic activity; cytotoxicity; nickel oxide.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / pharmacology
  • Antineoplastic Agents / pharmacology
  • Antioxidants / pharmacology
  • Humans
  • Metal Nanoparticles / chemistry*
  • Nickel / chemistry*
  • Plant Extracts / pharmacology

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents
  • Antioxidants
  • Plant Extracts
  • Nickel
  • nickel monoxide