Medical errors are an inevitable part of the professional activity of a medical worker: they were, are and will be, no matter what technological advances are introduced into medicine. For years, experts have recognized that there are medical errors and that society will compromise. But the desire to reduce their number is a real aim that requires serious efforts from both the medical community and government agencies responsible for the country's health. The aim of literature review was to analyze publications devoted to the study of the current state of methods of organizing and managing medical errors in Kazakhstan and some foreign countries. Analyzed full-text publications in English and Russian languages, which were devoted to the study of the prevalence and management of medical errors in Kazakhstan and abroad. According to the literature, there is an active medical and social policy aimed at organizing medical safety and improving the quality of life of patients, which is based on a set of measures of a socio-economic, legal and medical-organizational nature. A legislative and regulatory framework has been created and is being improved, including a number of laws, decrees, orders, standards of ministries and departments. Despite the above, the practice of managing and controlling medical errors as one of the mechanisms of medical safety is not well understood. Thus, all these issues remain relevant in general for world medical practice and initiate research in the interdisciplinary field of medical sciences and jurisprudence.