Histological and Radiological Features of a Four-Phase Injectable Synthetic Bone Graft in Guided Bone Regeneration: A Case Report

Marija Čandrlić; Željka Perić Kačarević; Zrinka Ivanišević; Matej Tomas; Aleksandar Včev; Dario Faj; Marko Matijević

doi:10.3390/ijerph18010206

Histological and Radiological Features of a Four-Phase Injectable Synthetic Bone Graft in Guided Bone Regeneration: A Case Report

Int J Environ Res Public Health. 2020 Dec 29;18(1):206. doi: 10.3390/ijerph18010206.

Authors

Marija Čandrlić^{1

2}, Željka Perić Kačarević³, Zrinka Ivanišević¹, Matej Tomas¹, Aleksandar Včev⁴, Dario Faj⁵, Marko Matijević¹

Affiliations

¹ Department of Dental Medicine, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, 31 000 Osijek, Croatia.
² Faculty of Medicine Osijek, J.J. Strossmayer University of Osijek, 31 000 Osijek, Croatia.
³ Department of Anatomy, Histology, Embriology, Pathology Anatomy and Pathology Histology, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, 31 000 Osijek, Croatia.
⁴ Department of Pathophysiology, Physiology and Immunology, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, 31 000 Osijek, Croatia.
⁵ Department of Biophysics and Radiology, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, 31 000 Osijek, Croatia.

Abstract

Background and objective: Injectable synthetic bone grafts (ISBG) are widely used biomaterials for regeneration purposes. The aim of this case report was to examine the efficacy of ISBG in the management of buccal fenestration in the case of a 25-year-old female.

Case report: After a traumatic tooth extraction, the defect was filled with ISBG and covered with a resorbable membrane. The ISBG showed easy handling and the patient had no complications during healing. Six months after augmentation, a bone biopsy was taken during implant bed preparation. The histological results showed good integration of ISBG into the newly formed bone and no signs of tissue inflammation. Additionally, a CBCT (cone beam computed tomography) analysis was performed to support the histological results.

Conclusion: The use of the examined ISBG led to successful treatment of the buccal fenestration defect.

Keywords: biomaterial; guided bone regeneration; injectable synthetic bone graft; tissue engineering.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Alveolar Ridge Augmentation*
Biocompatible Materials
Bone Regeneration*
Cross-Sectional Studies
Female
Guided Tissue Regeneration, Periodontal*
Humans
Tooth Extraction

Substances

Biocompatible Materials