Considerable methods have so far been used for the surface modification of biomedical membranes. Several reviews and articles have been published on the improvements achieved in the field of poly(arylsulfone) membranes subjected to various surface modification methods and used in biomedical applications. This review concentrates on the surface modification, biological applications and future perspective of the poly(arylsulfone) biomedical membranes. Different surface modification procedures employed for the poly(arylsulfone) membranes have been classified, studied and compared. Diverse surface modification techniques include surface coating, chemical modification and immobilization/cross-linking, grafting, surface zwitterionicalization, mussel-inspired coating and layer-by-layer assembly. Furthermore, we review the recent research studies performed on the surface modification of the poly(arylsulfone) biomedical membranes. Meanwhile, the properties of biomedical membranes are also discussed in each section. At last, the future perspective and challenges of the strategies utilized for the surface modification of poly(arylsulfone) biomedical membranes are presented.
Keywords: hemocompatibility; Poly(arylsulfone); biomedical membrane; cytocompatibility; surface modification.