ALK3 Is Not Required for the Embryonic Development, Homeostasis, and Repopulation of Epidermal Langerhans Cells in Steady and Inflammatory States

J Invest Dermatol. 2021 Jul;141(7):1858-1861. doi: 10.1016/j.jid.2020.10.028. Epub 2020 Dec 23.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Morphogenetic Protein 7 / metabolism
  • Bone Morphogenetic Protein Receptors, Type I / deficiency*
  • Bone Morphogenetic Protein Receptors, Type I / genetics
  • Disease Models, Animal
  • Embryo, Mammalian
  • Embryonic Development*
  • Homeostasis
  • Humans
  • Imiquimod / administration & dosage
  • Imiquimod / immunology
  • Langerhans Cells / physiology*
  • Mice
  • Mice, Knockout
  • Psoriasis / diagnosis
  • Psoriasis / immunology*
  • Psoriasis / pathology
  • Severity of Illness Index
  • Signal Transduction / immunology

Substances

  • Bone Morphogenetic Protein 7
  • bmp7 protein, mouse
  • Bmpr1a protein, mouse
  • Bone Morphogenetic Protein Receptors, Type I
  • Imiquimod