SARS CoV2 infection in a young subject affected by arginosuccinate synthase deficiency: A case report of epilepsy worsening

N Vitturi; L Lenzini; F Francini-Pesenti; G Gugelmo; A Avogaro

doi:10.1016/j.ymgmr.2020.100698

SARS CoV2 infection in a young subject affected by arginosuccinate synthase deficiency: A case report of epilepsy worsening

Mol Genet Metab Rep. 2020 Dec 11:26:100698. doi: 10.1016/j.ymgmr.2020.100698. eCollection 2021 Mar.

Authors

N Vitturi¹, L Lenzini², F Francini-Pesenti³, G Gugelmo³, A Avogaro¹

Affiliations

¹ University of Padova, Department of Medicine-DIMED, Division of Metabolic Diseases, University Hospital, Padova, Italy.
² University of Padova, Department of Medicine-DIMED, Emergency and Hypertension Unit, University Hospital, Padova, Italy.
³ University of Padova, Department of Medicine-DIMED, Division of Clinical Nutrition, University Hospital, Padova, Italy.

Abstract

We describe a case of a 21 years old woman affected by Citrullinemia type 1- Arginosuccinate Synthase deficiency (ASSD)-who underwent a SARS CoV2 infection during the first phase of pandemic burst in Italy. She had no symptoms of infection nor a metabolic crisis. After recovery from SARS CoV2, she experienced a worsening in their epilepsy despite therapy, with one/two crisis a week.

Keywords: Epilepsy; Inherited metabolic diseases; Metabolic crisis; SARS-CoV2; Seizures; Urea cycle disorders.

Publication types

Case Reports