Effects of interaction between enrofloxacin and copper on soil enzyme activity and evaluation of comprehensive toxicity

Rui Yang; Jinhua Wang; Lusheng Zhu; Jun Wang; Lili Yang; Shushuai Mao; Jeremy L Conkle; Yangyang Chen; Young Mo Kim

doi:10.1016/j.chemosphere.2020.129208

Effects of interaction between enrofloxacin and copper on soil enzyme activity and evaluation of comprehensive toxicity

Chemosphere. 2021 Apr:268:129208. doi: 10.1016/j.chemosphere.2020.129208. Epub 2020 Dec 15.

Authors

Rui Yang¹, Jinhua Wang², Lusheng Zhu³, Jun Wang⁴, Lili Yang⁵, Shushuai Mao⁶, Jeremy L Conkle⁷, Yangyang Chen⁸, Young Mo Kim⁹

Affiliations

¹ Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: ryang_1986@163.com.
² Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: wjh@sdau.edu.cn.
³ Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: lushzhu@sdau.edu.cn.
⁴ Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: jwang@sdau.edu.cn.
⁵ Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: 1021374147@qq.com.
⁶ Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: 798487054@qq.com.
⁷ Department of Physical & Environmental Sciences, Texas A&M University-Corpus Christi, Corpus Christi, TX, 78412, USA. Electronic address: Jeremy.Conkle@tamucc.edu.
⁸ Key Laboratory of Agricultural Environment in Universities of Shandong, College of Resources and Environment, Shandong Agricultural University, Taian, 271018, PR China. Electronic address: chenyangyang_1988@163.com.
⁹ Department of Civil and Environmental Engineering, Hanyang University, Seongdong-gu, Seoul, 04763, Republic of Korea. Electronic address: youngmo@hanyang.ac.kr.

PMID: 33352514
DOI: 10.1016/j.chemosphere.2020.129208

Abstract

Antibiotics are detected in association with heavy metals in the soil. However, interactions between antibiotics and heavy metals on soil enzyme activity have yet to been studied thoroughly. In this study, soil enzyme activity (urease, sucrase, phosphatase, and Rubisco) were measured after exposure to soils dosed with copper (Cu) and/or enrofloxacin (ENR) over 28 days. Enzyme responses to ENR only treatments varied, but Cu exhibited a strong negative response from all soil enzymes except Rubisco. An interaction between the effects of the two pollutants on soil enzymes was observed in the combined contamination treatments. Greater comprehensive toxicity to soil enzyme activity was observed in combined treatment groups compared to other groups. We anticipate our studies can provide a scientific theoretical basis for the combined pollution of antibiotics and heavy metals in soil.

Keywords: Comprehensive toxicity; Copper; Enrofloxacin; Interaction; Soil enzymatic activity.

MeSH terms

Copper / analysis
Copper / toxicity
Enrofloxacin
Metals, Heavy* / analysis
Soil
Soil Pollutants* / analysis
Soil Pollutants* / toxicity

Substances

Metals, Heavy
Soil
Soil Pollutants
Enrofloxacin
Copper