CLL dedifferentiation to clonally related myeloid cells

Blood Adv. 2020 Dec 22;4(24):6169-6174. doi: 10.1182/bloodadvances.2020002726.

Abstract

  1. Common progenitor cells exist in clonally related concomitant chronic lymphocytic leukemia and acute myeloid leukemias.

  2. CLL cells dedifferentiated to clonally related myeloid cells posttransplantation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cell Transformation, Neoplastic
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell* / genetics
  • Myeloid Cells