Analysis of risk factors for perioperative death in patients undergoing aortic valve replacement using biological valves

Medicine (Baltimore). 2020 Dec 24;99(52):e23909. doi: 10.1097/MD.0000000000023909.

Abstract

Background: Aortic valve disease has become one of the important factors affecting human health. Aortic valve disease is a progressive disease, if not actively treated, the prognosis is poor. Aortic valve replacement (AVR) surgery is an important treatment for aortic valve disease. At present, the AVR surgery using biological valve accounts for about 40% of the total number of AVR surgery. There are still more perioperative deaths in China due to the large number of AVR patients using biological valves. The objective of this study is to explore measures to reduce perioperative mortality of patients after AVR surgery with biological valves.

Methods: The clinical data of patients undergoing AVR surgery with biological valves in Affiliated Hospital of Qingdao University from November 15, 2020 to December 31, 2022 were reviewed and analyzed. Patients were divided into death group and survival group according to their perioperative survival. Risk factors that may influence perioperative mortality were analyzed and compared between the 2 groups.

Discussion: This study was a retrospective analysis of risk factors that may influence perioperative mortality in patients undergoing AVR surgery using biological valves. The conclusions of this study can be used to guide clinical decisions-making and relevant guidelines-developing for perioperative treatment of patients undergoing AVR surgery using biological valves.

MeSH terms

  • Aortic Valve Disease* / diagnosis
  • Aortic Valve Disease* / mortality
  • Aortic Valve Disease* / surgery
  • Aortic Valve* / diagnostic imaging
  • Aortic Valve* / surgery
  • Bioprosthesis*
  • China / epidemiology
  • Echocardiography / methods
  • Female
  • Heart Valve Prosthesis Implantation* / instrumentation
  • Heart Valve Prosthesis Implantation* / methods
  • Heart Valve Prosthesis Implantation* / mortality
  • Heart Valve Prosthesis*
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Perioperative Period / mortality
  • Prognosis
  • Retrospective Studies
  • Risk Assessment / methods
  • Risk Factors