Breast metastasis from medullary carcinoma of thyroid: A case report with literature view

J Pak Med Assoc. 2020 Nov;70(11):2051-2053. doi: 10.5455/JPMA.48120.

Abstract

Primary Breast cancer is the most common malignancy in females but secondary involvement of breast is very rare. The Most common sites of primaries for breast metastasis are breast carcinoma of contra lateral side, Lymphoma and leukaemia. Medullary Thyroid Carcinoma (MTC) itself is rare and commonly metastasises to liver, lung and bones. Secondary breast involvement by MTC is very rare with only few case reports in literature. Clinically and radiographically breast secondaries mimic benign lesions and may cause diagnostic challenges. To avoid unnecessary surgery and for appropriate treatment decision,accurate diagnosis is important. We present here our experience of a similar case of secondary breast carcinoma from MTC seen at MINAR cancer hospital Multan. The patient presented clinically and radiologically with benign breast lumps. Fine needle aspiration (FNAC) showed atypical cells and Ultra sound guided Trucut biopsy confirmed it to be a secondary from MTC. Patient is under treatment of an oncologist, has been treated with chemotherapy and is on follow up till date.

Keywords: Breast metastasis, medullary carcinoma of thyroid, Fine needle aspiration, Mammography..

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms* / therapy
  • Carcinoma, Medullary* / diagnostic imaging
  • Carcinoma, Neuroendocrine* / diagnostic imaging
  • Carcinoma, Neuroendocrine* / therapy
  • Female
  • Humans
  • Thyroid Neoplasms*