Microfluidic High-Throughput Platforms for Discovery of Novel Materials

Nanomaterials (Basel). 2020 Dec 15;10(12):2514. doi: 10.3390/nano10122514.

Abstract

High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed.

Keywords: high-throughput platforms; materials screening; micro/nano-structures; microarray; microfluidic droplet.

Publication types

  • Review