Method Limitations in LC-MS/MS and Immunonephelometric Measurement of IgG Subclasses

Clin Chem. 2021 Jan 30;67(2):440-441. doi: 10.1093/clinchem/hvaa303.

Grace van der Gugten¹, Andre Mattman^{1

2}, Gordon Ritchie^{1

2}, Luke Y C Chen^{2

3}, Alex Chin^{4

5}, Daniel T Holmes^{1

2}, John R Mills⁶, Lokinendi V Rao^{7

8}

¹ Department of Pathology and Laboratory Medicine, St Paul's Hospital, Vancouver, BC, Canada.
² Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
³ Division of Hematology, Vancouver General Hospital, Vancouver, BC, Canada.
⁴ Department of Pathology and Laboratory Medicine, Calgary Laboratory Services, Calgary, AB, Canada.
⁵ Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
⁶ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
⁷ Quest Diagnostics, North Region, Marlborough, MA, USA.
⁸ University of Massachusetts Medical School, Worcester, MA, USA.

No abstract available

Keywords: IgG4; SNP; analytical interference; mass spectrometry.

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