Clinical characteristics and outcomes of adults with peripheral extracorporeal membrane oxygenation in a developing country: A single center 8-year retrospective study

Perfusion. 2022 Jan;37(1):31-36. doi: 10.1177/0267659120980376. Epub 2020 Dec 16.

Abstract

Introduction: In our institute, we began using peripheral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) in 2010, and peripheral veno-venous (VV) ECMO in 2015. This study aimed to describe clinical characteristics and outcomes in those patients.

Methods: We reviewed retrospective data of adults receiving peripheral ECMO from January 2010 to December 2017 and divided it into two groups for analysis: VA- and VV-ECMO.

Results: There were 28 patients in the VA group and 12 in VV. For VA, the mean (SD) age was 58.5 (17.2) years. The most common indication was cardiac arrest (12 patients, 42.9%); 15 patients (53.6%) were on intra-aortic balloon pump concomitantly. In the VV cohort, the mean age was 53.3 (16.2) years. Eleven (91.7%) patients had acute respiratory distress syndrome as an indication. The mortality rate of VA-ECMO was 85.7%, and VV was 58.3%.

Conclusion: The mortality rate in our ECMO center was considerably higher than that in the international registry report. Improved team education, rigid patient selection criteria, and a reimbursement protocol should lead to ameliorated outcomes.

Trial registration: TCTR20190120001. Registered January 19, 2019.

Keywords: acute respiratory distress syndrome; cardiac arrest; cardiogenic shock; extracorporeal membrane oxygenation; respiratory failure.

MeSH terms

  • Adult
  • Developing Countries
  • Extracorporeal Membrane Oxygenation* / methods
  • Humans
  • Intra-Aortic Balloon Pumping
  • Middle Aged
  • Respiratory Distress Syndrome* / therapy
  • Retrospective Studies