Management of acute corneal hydrops with intracameral gas injection

Jamasb J Sayadi; Helene Lam; Charles C Lin; David Myung

doi:10.1016/j.ajoc.2020.100994

Management of acute corneal hydrops with intracameral gas injection

Am J Ophthalmol Case Rep. 2020 Nov 23:20:100994. doi: 10.1016/j.ajoc.2020.100994. eCollection 2020 Dec.

Authors

Jamasb J Sayadi^{1

2}, Helene Lam^{1

2}, Charles C Lin¹, David Myung^{1

2

3}

Affiliations

¹ Byers Eye Institute at Stanford, 2452 Watson Ct, Palo Alto, CA, 94303, USA.
² VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA, 94304, USA.
³ Department of Chemical Engineering, Stanford, CA, 94305, USA.

Abstract

Purpose: To report two cases of severe acute corneal hydrops that were resolved by intracameral gas injection alone.

Observations: Case 1 is a 27-year-old woman with bilateral severe keratoconus who developed sequential acute corneal hydrops in the right eye followed by the left eye that were each successfully treated using intracameral 20% sulfur hexafluoride gas injection. Case 2 is a 62-year-old man that developed a large fluid cleft beneath a pre-existing LASIK flap, which resolved with intracameral 20% sulfur hexafluoride gas injection without the need for corneal transplantation.

Conclusions and importance: In acute corneal hydrops, intracameral gas injection to tamponade Descemet's membrane tears with decompression of stromal fluid can be an effective intervention to delay or avoid keratoplasty in individuals whose corneal hydrops does not improve with conventional medical management.

Keywords: Acute corneal hydrops; Descemet's membrane; Intracameral gas injection; Keratoconus; LASIK; Sulfur hexafluoride.

Publication types

Case Reports

Grants and funding

P30 EY026877/EY/NEI NIH HHS/United States