Diagnostic Accuracy of Intraoperative Frozen Section Analysis in Correlation with Histopathological Diagnosis of Ovarian Tumors in a Tertiary Care Center - A Retrospective Study

Cancer Invest. 2021 Feb;39(2):153-158. doi: 10.1080/07357907.2020.1865395. Epub 2020 Dec 28.

Abstract

Treatment plan for ovarian neoplasms differs for benign, borderline and malignant tumors. With a turnaround time of 15-20 minutes, frozen section has become a reliable intraoperative diagnostic tool. The aim of this study is to correlate the frozen section diagnosis with subsequent histopathologic diagnosis and determine the accuracy of frozen section diagnosis. The study included 152 ovarian tumors, the overall accuracy of frozen section in diagnosing malignancy was 99.34%, whereas that for benign and borderline tumors were 97.37% and 96.71% respectively. However, the accuracy, sensitivity and specificity for borderline tumors and mucinous tumors were found to be low.

Keywords: Intraoperative frozen section; Mucinous tumors; Ovarian tumor; accuracy.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Female
  • Frozen Sections / methods*
  • Humans
  • Intraoperative Period
  • Middle Aged
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery*
  • Retrospective Studies
  • Sensitivity and Specificity
  • Tertiary Care Centers
  • Young Adult