A longitudinal observation of general psychopathology before the COVID-19 outbreak and during lockdown in Italy

J Psychosom Res. 2021 Feb:141:110328. doi: 10.1016/j.jpsychores.2020.110328. Epub 2020 Dec 4.

Abstract

Objective: Italy has been largely involved by the COVID-19 pandemic. The present study aimed at evaluating the impact of the lockdown during the pandemic on mental health adopting both a longitudinal and a cross-sectional design. Accordingly, the study investigated general psychopathology a few weeks before the COVID-19 outbreak (T0) and during lockdown (T1), and the associations between lockdown-related environmental conditions, self-perceived worsening in daily living and psychopathology.

Methods: 130 subjects (aged 18-60 years) were included in the longitudinal design, and an additional subsample of 541 subjects was recruited for the in-lockdown evaluation. Socio-demographic data and the Brief Symptom Inventory were collected both at T0 and T1. Moreover, at T1 an online survey was administered for the evaluation of lockdown-related environmental conditions and self-perceived variations in daily living induced by quarantine, along with the Impact of Event Scale-Revised.

Results: Longitudinal analysis showed that phobic anxiety and depressive symptoms increased at T1 as compared with T0, whereas interpersonal sensitivity and paranoid ideation decreased. Pre-existing general psychopathology predicted COVID-19-related post-traumatic symptomatology. Cross-sectional analyses underlined that self-perceived deteriorations in various areas of daily living were associated with general and post-traumatic psychopathology, and with several lockdown-related conditions, especially economic damage.

Conclusion: The present study underlined a different trend of increased internalizing and decreased interpersonal symptoms during COVID-19 quarantine in Italy. Furthermore, the results showed that subjects with pre-existing psychopathology and those reporting economic damage during the pandemic were more likely to develop deterioration of their mental health.

Keywords: Covid-19; Depression; Lockdown; Pandemic; Post-traumatic stress disorders; Quarantine.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control*
  • Cross-Sectional Studies
  • Disease Outbreaks*
  • Female
  • Humans
  • Italy / epidemiology
  • Longitudinal Studies
  • Male
  • Mental Disorders / epidemiology*
  • Middle Aged
  • Quarantine / psychology*
  • Surveys and Questionnaires
  • Young Adult