[Preliminary study on the antimutagenesis of vegetables and fruits]

H Z Luo; S J Cheng; Y Z Jang; N J Han; X Q Li; S Y Yie; J L Liang

[Preliminary study on the antimutagenesis of vegetables and fruits]

Zhonghua Zhong Liu Za Zhi. 1987 Sep;9(5):328-32.

[Article in Chinese]

Authors

H Z Luo¹, S J Cheng, Y Z Jang, N J Han, X Q Li, S Y Yie, J L Liang

Affiliation

¹ Cancer Institute, Chinese Academy of Medical Sciences, Beijing.

PMID: 3330707

Abstract

Possible antimutation of 108 preparations of 91 kinds of vegetables and fruits on Salmonella typhimurium TA98 and TA100 mutants was tested. 4-nitroquinoline-N-oxide (4 NQO), N-methyl-N-nitro-N-nitrosoguanidine (MNNG), aflatoxin B1 (AFB1) and benzo (a) pyrene (BaP) were used as mutagens. The results showed that 67 (62%) preparations had antimutagenic action in vitro to different degrees. 9.6% of all preparations showed inhibition action on 4 NQO in TA100 mutant and 12.3%, in TA98, 5% on MNNG in TA100, 38% on AFB1 in TA100 and 45.1% in TA98, 28.9% on BaP in TA100. This experiment provides a scientific basis to the study of food resources as prevention of carcinogenesis.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Fruit*
Male
Mutagenicity Tests / methods
Mutation*
Rats
Salmonella typhimurium / genetics
Vegetables*