Biliary Dyskinesia: Current Perspectives and Future Directions

Am Surg. 2021 Jun;87(6):954-960. doi: 10.1177/0003134820971617. Epub 2020 Dec 9.

Abstract

Biliary dyskinesia (BD) is a disorder characterized by functional biliary pain, the absence of gallstones on ultrasound, and the finding of a reduced gallbladder ejection fraction on a cholecystokinin-cholescintigraphic scan. Cholecystectomy remains a commonly applied treatment for BD, despite a lack of high-quality evidence supporting the practice. The following article provides an overview of the current diagnostic strategies, treatment outcomes with both surgical and nonsurgical treatment, emerging considerations related to special populations, and suggestions for addressing the identified knowledge gaps, moving forward in an effort to develop stronger, more evidence-based practice guidelines for treating this poorly understood and poorly studied condition.

Keywords: biliary dyskinesia; cholecystokinin; gallbladder; gallbladder ejection fraction.

Publication types

  • Review

MeSH terms

  • Biliary Dyskinesia / diagnosis*
  • Biliary Dyskinesia / surgery*
  • Cholecystectomy
  • Cholelithiasis / surgery
  • Conservative Treatment
  • Diagnosis, Differential
  • Diagnostic Imaging
  • Digestive System Surgical Procedures*
  • Humans
  • Pain Measurement