An overview of the effect of bioaerosol size in coronavirus disease 2019 transmission

Int J Health Plann Manage. 2021 Mar;36(2):257-266. doi: 10.1002/hpm.3095. Epub 2020 Dec 8.

Abstract

The fast spread of coronavirus disease 2019 (COVID-19) constitutes a worldwide challenge to the public health, educational and trade systems, affecting the overall well-being of human societies. The high transmission and mortality rates of this virus, and the unavailability of a vaccine or treatment, resulted in the decision of multiple governments to enact measures of social distancing. Such measures can reduce the exposure to bioaerosols, which can result in pathogen deposition in the respiratory tract of the host causing disease and an immunological response. Thus, it is important to consider the validity of the proposal for keeping a distance of at least 2 m from other persons to avoid the spread of COVID-19. This work reviews the effect of aerodynamic diameter (size) of particles carrying RNA copies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A SARS-CoV-2 carrier person talking, sneezing or coughing at distance of 2 m can still provide a pathogenic bioaerosol load with submicron particles that remain viable in air for up to 3 h for exposure of healthy persons near and far from the source in a stagnant environment. The deposited bioaerosol creates contaminated surfaces, which if touched can act as a path to introduce the pathogen by mouth, nose or eyes and cause disease.

Keywords: COVID-19; SARS-CoV-2; aerodynamic size; bioaerosol; infection; social distancing; virus.

Publication types

  • Review

MeSH terms

  • Aerosols / adverse effects*
  • COVID-19 / transmission*
  • Humans
  • Particle Size
  • RNA, Viral / adverse effects
  • Respiratory System / virology
  • SARS-CoV-2 / pathogenicity*
  • SARS-CoV-2 / ultrastructure

Substances

  • Aerosols
  • RNA, Viral