Application of machine intelligence technology in the detection of vaccines and medicines for SARS-CoV-2

Eur Rev Med Pharmacol Sci. 2020 Nov;24(22):11977-11981. doi: 10.26355/eurrev_202011_23860.

Abstract

Researchers have found many similarities between the 2003 severe acute respiratory syndrome (SARS) virus and SARS-CoV-19 through existing data that reveal the SARS's cause. Artificial intelligence (AI) learning models can be created to predict drug structures that can be used to treat COVID-19. Despite the effectively demonstrated repurposed drugs, more repurposed drugs should be recognized. Furthermore, technological advancements have been helpful in the battle against COVID-19. Machine intelligence technology can support this procedure by rapidly determining adequate and effective drugs against COVID-19 and by overcoming any barrier between a large number of repurposed drugs, laboratory/clinical testing, and final drug authorization. This paper reviews the proposed vaccines and medicines for SARS-CoV-2 and the current application of AI in drug repurposing for COVID-19 treatment.

Publication types

  • Review

MeSH terms

  • Adenosine Monophosphate / analogs & derivatives
  • Adenosine Monophosphate / therapeutic use
  • Alanine / analogs & derivatives
  • Alanine / therapeutic use
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Antiviral Agents / therapeutic use
  • Artificial Intelligence*
  • Ascorbic Acid / therapeutic use
  • COVID-19 / prevention & control
  • COVID-19 Drug Treatment*
  • COVID-19 Vaccines / therapeutic use
  • Chloroquine / therapeutic use
  • Deep Learning
  • Drug Combinations
  • Drug Development*
  • Drug Repositioning*
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Immunosuppressive Agents / therapeutic use
  • Lopinavir / therapeutic use
  • Machine Learning
  • Ribavirin / therapeutic use
  • Ritonavir / therapeutic use
  • Vitamins / therapeutic use

Substances

  • Antibodies, Monoclonal, Humanized
  • Antiviral Agents
  • COVID-19 Vaccines
  • Drug Combinations
  • Immunosuppressive Agents
  • Vitamins
  • lopinavir-ritonavir drug combination
  • Lopinavir
  • remdesivir
  • Adenosine Monophosphate
  • Ribavirin
  • Hydroxychloroquine
  • Chloroquine
  • tocilizumab
  • Ritonavir
  • Alanine
  • Ascorbic Acid